The techniques used to measure esophageal and sphincter physiology have evolved over time with high-resolution manometry and the functional luminal imaging probe (FLIP)
taking center stage over the past 10 years. Currently high-resolution manometry in combination with the Chicago Classification v3.0 is the “Gold Standard” for the clinical
assessment of esophageal motility disorders.
However, a growing body of literature surrounding the use of the functional luminal imaging probe has demonstrated its clinical utility as both a diagnostic tool and as a device which can be used to guide and measure response to therapy.