The techniques used to measure esophageal and sphincter physiology have evolved over time with high-resolution manometry and the functional luminal imaging probe (FLIP) 
taking center stage over the past 10 years. Currently high-resolution manometry in combination with the Chicago Classification v3.0 is the “Gold Standard” for the clinical 
assessment of esophageal motility disorders.
 However, a growing body of literature surrounding the use of the functional luminal imaging probe has demonstrated its clinical utility as both a diagnostic tool and as a device which can be used to guide and measure response to therapy.

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